Figure 2 | Scientific Reports

Figure 2

From: Deficiency in Toll-interacting protein (Tollip) skews inflamed yet incompetent innate leukocytes in vivo during DSS-induced septic colitis

Figure 2

Tollip−/− mice showed enhanced pro-inflammatory response both on systemic and local level after challenged with DSS.

(A,B) TNT-a, IL-1β, IL-6 and IL-10 levels in plasma and colon culture supernatant from WT and Tollip deficient mice. WT control n = 5; Tollip−/− control n = 7; DSS treated WT (day 6), n = 7; DSS treated Tollip−/− (day 6), n = 7; DSS treated WT (day 12), n = 7; DSS treated Tollip−/− (day 12), n = 4. *P < 0.05, ** P < 0.01, *** P < 0.01.

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