Figure 4
From: NLRP3 inflammasome mediates contrast media-induced acute kidney injury by regulating cell apoptosis
NLRP3 deficiency effect on contrast-induced histological injury in vivo.
(a) Represented image of hematoxylin and eosin (H&E) staining in the tubular (black arrows indicating the injury). (b) Tubular injury score in the outer medulla was determined. 1. control; 2. Model undergoing unilateral nephrectomy; 3. Model + water deprivation for one day; 4. Model + water deprivation for one day + Furosemide; 5. Model + water deprivation + Furosemide + contrast media. Data are shown as mean ± SD. **P < 0.01, ***P < 0.001.
