Table 2 The 30 most significantly downregulated mRNAs in psoriatic-like lesions from 20-week-old K14-Angptl6 Tg relative to wild-type littermate mice.

From: Upregulation of ANGPTL6 in mouse keratinocytes enhances susceptibility to psoriasis

 

Symbol

log2 (fold change)

p-value

1

Klrk1

−8.63

<0.001

2

Srgap1

−5.77

<0.005

3

Tmem165

−5.22

<0.001

4

LOC100502803

−5.08

<0.01

5

Mx1

−4.87

<0.001

6

Kcnh6

−4.75

<0.001

7

Pyy

−4.59

<0.001

8

Gm11596

−4.34

<0.001

9

Cyp2a5

−4.23

<0.001

10

LOC16697

−4.23

<0.001

11

Gm11555

−4.20

<0.001

12

Muc4

−4.09

<0.001

13

Paqr7

−4.07

<0.001

14

Wdr4

−4.06

<0.001

15

Alox15

−3.99

<0.001

16

Gm4553

−3.99

<0.001

17

Klri2

−3.95

<0.001

18

Krt74

−3.94

<0.001

19

1110032F04Rik

−3.91

<0.001

20

AK044745

−3.91

<0.005

21

AK162617

−3.91

<0.001

22

D830012I16Rik

−3.91

<0.001

23

Gm2696

−3.89

<0.001

24

Krtap4-16

−3.86

<0.001

25

Sftpb

−3.86

<0.001

26

Gjd3

−3.83

<0.001

27

5033406O09Rik

−3.81

<0.001

28

AK042705

−3.81

<0.001

29

Tsks

−3.81

<0.001

30

Ltbp1

−3.74

<0.001

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