Figure 5 | Scientific Reports

Figure 5

From: Metabolomics reveals the mechanisms for the cardiotoxicity of Pinelliae Rhizoma and the toxicity-reducing effect of processing

Figure 5

Molecular networks and the canonical pathways in the serum of raw PR- and PRZA-treated rats.

(A) Raw PR group; (B) PRZA group. The network was gained by overlapping raw PR- or PRZA-treated group’s data to control group’s data. Metabolites are represented as nodes, and the biological relationship between two nodes is represented as a line. The colored symbols represent metabolites that occurring in the tested data, while the transparent entries are molecules from the Ingenuity Knowledge Database. Orange symbols represent up-regulated metabolites; green symbols represent down-regulated metabolites. Solid lines between molecules indicate a direct physical relationship between molecules; dotted lines indicate indirect functional relationships.

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