Table 1 Characteristics of the study participants.

From: Elevation in fibroblast growth factor 23 and its value for identifying subclinical atherosclerosis in first-degree relatives of patients with diabetes

Variable

Total

Without an FHD

With a first-degree FHD

Gender (men/women)

596/1123

507/900

89/223*

Age (years)

52.82 (46.25–57.73)

53.08 (45.72–57.93)

52.26 (47.61–57.02)

BMI (kg/m2)

22.89 (20.94–24.89)

22.89 (20.95–24.87)

22.91 (20.86–25.07)

W (cm)

79.00 (73.00–86.00)

79.00 (73.00–86.00)

79.00 (72.13–85.88)

SBP (mmHg)

120.00 (110.00–128.67)

120.00 (110.00–129.33)

120.00 (110.00–128.50)

DBP (mmHg)

76.67 (70.00–80.67)

76.67 (70.00–80.67)

76.67 (70.00–80.67)

FPG (mmol/L)

5.13 ± 0.41

5.12 ± 0.41

5.18 ± 0.41*

2 hPG (mmol/L)

6.00 (5.21–6.79)

5.99 (5.17–6.76)

6.07 (5.28–6.88)

HbA1c (%)

5.5 (5.3–5.7)

5.5 (5.3–5.7)

5.6 (5.4–5.8)

FINS (mU/L)

6.55 (4.75–9.17)

6.46 (4.72–8.96)

7.15 (4.90–9.77)*

HOMA-IR

1.49 (1.05–2.11)

1.47 (1.04–2.09)

1.67 (1.12–2.32)

TC (mmol/L)

5.04 (4.43–5.74)

5.02 (4.42–5.69)

5.17 (4.52–5.89)

TG (mmol/L)

1.16 (0.81–1.63)

1.14 (0.80–1.63)

1.22 (0.86–1.67)

HDL-c (mmol/L)

1.45 (1.24–1.70)

1.46 (1.24–1.71)

1.42 (1.22–1.68)

LDL-c (mmol/L)

3.08 (2.57–3.62)

3.05 (2.52–3.57)

3.22 (2.69–3.74)

CRP (mg/L)

0.56 (0.28–1.17)

0.56 (0.27–1.14)

0.58 (0.28–1.24)

Ca (mmol/L)

2.33 (2.27–2.40)

2.33 (2.27–2.40)

2.34 (2.27–2.40)

eGFR (mL/min/1.73 m2)

99.19 ± 11.88

99.04 ± 12.10

99.86 ± 10.84

C-IMT (mm)

0.58 ± 0.10

0.58 ± 0.10

0.58 ± 0.10

Current smoker, n (%)

339 (19.72)

277 (19.69)

62 (19.87)

  1. Abbreviation: FHD: family history of diabetes; BMI: body mass index; W: waist circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; FPG: fasting plasma glucose; 2 hPG: 2-hour plasma glucose; HbA1c: glycated hemoglobin A1c; FINS: fasting serum insulin; HOMA-IR: homeostasis model assessment-insulin resistance; TC: total cholesterol; TG: triglyceride; HDL-c: high density lipoprotein cholesterol; LDL-c: low density lipoprotein cholesterol; CRP: C-reactive protein; Ca: Serum calcium; eGFR: estimated glomerular filtration rate. Data are means ± SD, median (interquartile range) or N (%).
  2. *P < 0.05 versus subjects without an FHD; P < 0.01 versus subjects without an FHD.