Table 2 Results of the multivariable Cox regression analysis for the overall incidence of atrial fibrillation (n = 10,731).

From: Evaluation of the Association Between Retinal Vein Occlusion and the Risk of Atrial Fibrillation Development: A 12-Year, Retrospective Nationwide Cohort Study

Variables

Multivariable cox

adjusted HR

95% CI

p-value

Group

 Comparison group

1 (ref)

  

 RVO group

1.35

1.09–1.67

0.006

Comorbidities (reference group: subjects without each comorbidity)

 Heart failure

3.26

2.65–4.02

<0.001

 Hyperthyroidism

1.87

1.09–3.19

0.022

 Acute Myocardial Infarction

1.55

1.00–2.41

0.049

 Cerebrovascular disease

1.30

1.03–1.64

0.027

 Hypertension

1.19

0.95–1.49

0.121

 Diabetes mellitus

1.13

0.92–1.38

0.247

 Chronic kidney disease

1.03

0.71–1.48

0.876

 Chronic lung disease

1.17

0.97–1.41

0.102

 Liver disease

1.24

1.01–1.54

0.044

Age group (year)

 <50

1 (ref)

  

 50~59

2.56

1.49–4.39

0.001

 60~69

3.56

2.13–5.97

<0.001

 70~79

6.65

3.94–11.24

<0.001

 ≥80

7.05

3.86–12.89

<0.001

Sex

 Male

1 (ref)

  

 Female

0.70

0.58–0.84

<0.001

Residence

 Seoul (metropolitan)

1 (ref)

  

 2nd area

1.14

0.86–1.52

0.362

 3rd area

0.94

0.71–1.25

0.681

 4th area

1.01

0.79–1.30

0.911

Household income

 0~30%

1 (ref)

  

 30–70%

1.07

0.83–1.38

0.602

 70–100%

0.97

0.76–1.22

0.773

  1. CI, confidence interval; RVO, retinal vein occlusion; HR, hazard ratio. Seoul, a metropolitan area in Korea; 2nd area included the largest province; 3rd area included the 2nd largest city and the 2nd and 3rd largest provinces; 4th area included other areas.
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