Figure 1
From: Prediction of phosphothreonine sites in human proteins by fusing different features
The schematic diagram of threonine phosphorylation.
Enzyme-catalyzed proton transfer from the nucleophilic (
) group on threonine attacks the γ-phosphate (
) group on ATP, resulting in transfer of the phosphate group to threonine to form phosphothreonine and ADP, while this transfer is facilitated by magnesium (Mg2+) and threonine kinase. (
) indicates the enzyme base that initiates proton transfer.
