Figure 1
Differences in the expression of hepatic miRNAs according to the stage of fibrosis in patients with chronic hepatitis B and C.
The expression of hepatic miR-20a, miR-21, miR-29a, miR-92a, miR-122, miR-146a, miR-221, miR-222, miR-224 was assessed by RT-qPCR from 1 ng of cDNA and compared in patients with F3-F4 and F0-F1-F2, in chronic hepatitis B patients (A–I) and in those with chronic hepatitis C (J–R). The ΔCt (ΔCt = 2ΔCp,sample) of each miRNA was calculated and normalized to the ΔCt value of SNORD44 in each biopsy. The log expression of the ratio miRNA/SNORD44 is shown as dot plot, each dot represents one patient (mean and standard deviation). The Wilcoxon rank-sum test was used to compare miRNAs expression.
