Table 3 Diagnostic performance of the miRNAs-based models to diagnose F3–F4 fibrosis in patients with CHB and CHC.
CHB model | AUC | 95% CI | p value |
---|---|---|---|
Serum miR-122 | 0.85 | 0.77–0.95 | |
Serum miR-222 | |||
Platelet count | |||
ALP | |||
APRI | 0.70 | 0.58–0.82 | 0.007 |
FIB-4 | 0.81 | 0.71–0.90 | 0.39 |
Hepatic miR-122 | 0.93 | 0.87–0.99 | |
Hepatic miR-224 | |||
Platelet count | |||
ALT | |||
Albumin | |||
APRI | 0.86 | 0.75–0.96 | 0.11 |
FIB-4 | 0.79 | 0.67–0.90 | 0.009 |