Figure 6
From: Effects of Melanocortin 3 and 4 Receptor Deficiency on Energy Homeostasis in Rats
Effect of MC3R and MC4R deficiency on glucose metabolism.
OGTT of different groups of rats at (a) 8 weeks and (b) 14 weeks of age. (c) Postprandial blood glucose (PBG) of mice at indicated ages. (d,e) Hb1Ac concentration, (f) Insulin and (g) Leptin levels of Mc3r KO, Mc4r KO, DKO and WT littermates at 14 week of age. Only data (mean ± SEM, n = 6–8) from males are shown. Females showed a similar trend. *p < 0.05, ***p < 0.001 vs. WT littermates (one-way ANOVA test).
