Figure 8 | Scientific Reports

Figure 8

From: Methazolamide improves neurological behavior by inhibition of neuron apoptosis in subarachnoid hemorrhage mice

Figure 8

Mathazolamide effectively inhibits ROS production in blood- or hemoglobin- induced primary cortical neurons.

PCNs grown in 96-well plates and exposed to blood (a, 2.5 μl blood are added to 97.5 μl medium with or without methazolamide) or hemoglobin (b, 5 μΜ hemoglobin, either with or without methazolamide) for 18 h. PCNs were trypsinized and centrifuged for 10 min at 3000 rpm. The supernatants were submitted for interacellular ROS (IU/ml) measurement. The quantitative analyses of interacellular ROS levels were shown. Data from 3 independent experiments.

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