Figure 8
The presence and regulation of DNM2 during mammalian spermatogenesis.
Spermatogenesis in the mouse model begins with the mitotic division of spermatogonial stem cells. These proliferating cells then enter meiosis I to become spermatocytes, followed by RS in meiosis II. Spermiogenesis promotes elongation of the RS into morphologically mature sperm. Throughout this process, DNM2 expression remains constant, with the potential regulating kinase, CDK1, expression high in early stage germ cells, and the regulating phosphatase, PPP3CA, high in late stage germ.
