Table 2 Elements concentration in CSF and serum of PD versus control.

From: Metallomic Biomarkers in Cerebrospinal fluid and Serum in patients with Parkinson’s disease in Indian population

Elements

CSF Concentration Average (±SD)

Serum Concentration Average (±SD)

Normal

PD

p-value

Normal

PD

p-value

Al

2.9 (±0.84)

2.45 (±1.47)

0.1701*

3.14 (±1.94)

4.29 (±2.06)

<0.00001*

Ca

25,921 (±5533)

28,130 (±3409)

0.03697*

65392.97 (±1755)

710950 (±2177)

<0.00001*

Co

0.12 (±0.093)

0.07 (±0.13)

<0.0001*

0.15 (±0.27)

0.14 (±0.29)

<0.00001

Cu

27.36 (±5.1

24.89 (±7.92)

0.03862*

1099 (±114.85)

891.82 (±197.93)

<0.00001*

Cr

0.98 (±0.63)

1.22 (±0.41)

0.04784*

0.71 (±0.72)

0.83 (±0.83)

0.07121

Fe

212.46 (±33.58)

182.88 (±89.28)

0.000323*

1205.49 (±316.09)

1155.55 (±264.94)

0.01231*

Pb

0.53 (±0.82)

0.97 (±0.98)

0.000801*

0.41 (±0.21)

0.49 (±0.37)

0.1161*

Mg

22,739.05 (±2386)

25,263 (±3433)

0.000114*

19883.8 (±1480.82)

20403.71 (±1244.19)

0.0002269*

Mn

1.07 (±0.81)

0.78 (±0.65)

0.08653*

1.35 (±1.17)

1.28 (±1.02)

0.3643

Si

83.69 (±35.64)

69.59 (±29.35)

0.08221*

402.6 (±105.73)

386.38 (±99.63)

0.02221

Zn

30.73 (±7.91

27.17 (±8.07

0.03259*

700.15 (±86.73)

687.39 (±81.14)

0.01592