Table 4 Elements concentration in CSF and serum of akinetic-dominant PD versus control.

From: Metallomic Biomarkers in Cerebrospinal fluid and Serum in patients with Parkinson’s disease in Indian population

Elements

CSF Concentration Average (±SD)

Serum Concentration Average (±SD)

Normal

PD

p-value

Normal

PD

p-value

Al

2.97 (±0.92)

2.56 (±1.58)

0.4889

2.97 (±2.27)

4.19 (±1.99)

<0.00001*

Ca

27372.0 (±3295.0)

28170.8 (±2633.7)

0.5946

65314.1 (±1899.8)

71063.7 (±2327.0)

<0.00001*

Co

0.085 ± 0.11

0.047 (±0.092)

<0.00001*

0.17 (±0.28)

0.13 (±0.22)

0.0281*

Cu

30.33 (±3.46)

24.59 (±7.039)

0.0026*

1066.54 (±130.65)

882.63 (±189.10)

<0.00001*

Cr

1.23 (±0.28)

1.20 (±0.36)

0.9309

0.60 (±0.54)

0.73 (±0.74)

0.17

Fe

214.54 (±43.81)

206.37 (±101.13)

0.2394

1260.82 (±300.91)

1169.84 (±267.19)

<0.00001*

Pb

0.87 (±0.72)

0.99 (±0.96)

0.7548

0.35 (±0.209)

0.53 (±0.38)

0.0002*

Mg

21899.3 (±1950.8)

25174.8 (±3651.9)

0.00095*

19715.0 (±1397)

20489.7 (±1401.1)

0.0004*

Mn

0.74 (±0.64)

0.73 (±0.63)

0.9931

1.33 (±0.94)

1.30 (±1.10)

0.4089

Si

70.01 (±24.38)

78.37 (±27.75)

0.06046

416.62 (±120.50)

389.41 (±104.18)

0.0341*

Zn

27.00 (±8.42)

26.43 (±8.56)

0.7228

685.50 (±96.17)

685.09 (±90.56)

0.9010