Figure 4 | Scientific Reports

Figure 4

From: Carbon Ion-Irradiated Hepatoma Cells Exhibit Coupling Interplay between Apoptotic Signaling and Morphological and Mechanical Remodeling

Figure 4

Correlations among variable parameters during apoptotic remodeling of HCCs and NHs.

(A) Cell shape vs mechanical properties. In detail, CPA vs E, in L02, r = 0.642, P = 0.00 < 0.01; in HepG2, r = 0.619, P = 0.00 < 0.01; in Smmc-7721, r = 0.519, P = 0.00 < 0.01; in Huh-7, r = 0.564, P = 0.00 < 0.01; in Mhcc-97L, r = 0.355, P = 0.005 < 0.01; (B) Cytoskeleton density vs mechanical properties. In detail, CD vs E, in L02, r = 0.872, P = 0.00 < 0.01; in HepG2, r = 0.790, P = 0.00 < 0.01; in Smmc-7721, r = 0.876, P = 0.00 < 0.01; in Huh-7, r = 0.866, P = 0.00 < 0.01; in Mhcc-97L, r = 0.724, P = 0.00 < 0.01; (C) Cell shape vs cytoskeleton density. In detail, CPA vs CD, in L02, r = 0.841, P = 0.00 < 0.01; in HepG2, r = 0.784, P = 0.00 < 0.01; in Smmc-7721, r = 0.700, P = 0.00 < 0.01; in Huh-7, r = 0.568, P = 0.00 < 0.01; in Mhcc-97L, r = 0.501, P = 0.003 < 0.01; (D) Caspase-3 protein levels vs mechanical properties. In detail, CPLs vs E, in L02, r = −0.811, P = 0.00 < 0.01; in HepG2, r = −0.784, P = 0.00 < 0.01; in Smmc-7721, r = −0.714, P = 0.00 < 0.01; in Huh-7, r = −0.747, P = 0.00 < 0.01; in Mhcc-97L, r = −0.701, P = 0.003 < 0.01.

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