Table 8 Incidence of Pregnancy, Perinatal Complications and Neonatal Outcomes in Singleton Spontaneously Conceived Pregnancies in Nulliparous Women to those who Conceived with ART.

From: Maternal and Live-birth Outcomes of Pregnancies following Assisted Reproductive Technology: A Retrospective Cohort Study

 

Singletons of ART Nulliparas (n = 1493)

Singletons of Control Nulliparas (n = 4255)

P

Pregnancy complications

GDM

177 (11.9)

262 (6.2)

<0.001

Gestational hypertension

109 (7.3)

137 (3.2)

<0.001

Preeclampsia

43 (2.9)

76 (1.8)

0.015

 mild preeclampsia

15 (1.0)

42 (1.0)

1

 severe preeclampsia

28 (1.9)

34 (0.8)

0.001

ICP

100 (6.7)

169 (4.0)

<0.001

Perinatal complications

Placenta previa

101 (6.8)

111 (2.6)

<0.001

 complete placenta previa

36 (2.4)

26 (0.6)

<0.001

 partial placenta previa

8 (0.5)

4 (0.1)

0.004

 marginal placenta previa

57 (3.8)

81 (1.9)

<0.001

Placental abruption

19 (1.3)

11 (0.3)

<0.001

pPROM

75 (5.0)

103 (2.4)

<0.001

Abnormal placental cord insertion

62 (4.2)

130 (3.1)

0.045

Placental adherence

96 (6.4)

112 (2.6)

<0.001

Postpartum haemorrhage

62 (4.2)

94 (2.2)

<0.001

Polyhydramnios

30 (2.0)

49 (1.2)

0.019

Oligohydramnios

105 (7.0)

305 (7.2)

0.907

Neonatal Outcomes

Preterm labour

255 (17.1)

294 (6.9)

<0.001

Low birthweight

154 (10.3)

204 (4.8)

<0.001

Macrosomia

108 (7.2)

312 (7.3)

0.954

Small for date infant

15 (1.0)

40 (0.9)

0.877

1 minute Apgar ≤ 7

56 (3.8)

106 (2.5)

0.014

5 minute Apgar ≤ 7

11 (0.7)

6 (0.1)

0.001

  1. Note: Data are n (%). ART, assisted reproductive technology; GDM, gestational diabetes mellitus; ICP, intrahepatic cholestasis of pregnancy; pPROM, preterm premature rupture of membranes.