Table 2 Effect of melatonin on female fertility.

From: Melatonin improves age-induced fertility decline and attenuates ovarian mitochondrial oxidative stress in mice

Length of treatment (mo)

Groups

No. of mice examined

No. of mice with vaginal plug

No. of mice bearing pups

Total number

Average litter size of pregnant mice

6

Vehicle

23

19

17

109

6.5 ± 2.3

Melatonin

21

20

20

162

7.1 ± 1.8

12

Vehicle

29

22

11

32

2.9 ± 1.6

Melatonin

25

21

16

90

5.7 ± 2.2**

  1. *P < 0.05, **P < 0.05 versus vehicle; values are mean ± SD.
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