Table 4 Effect of melatonin on in vitro maturation of GV oocytes.
Length of treatment (mo) | Groups | No. of mice examined | No. of oocytes cultured | Maturation stage examined in 16–18 h of culture (%) | ||
---|---|---|---|---|---|---|
GV | MI | MII | ||||
6 | Vehicle | 13 | 395 | 34 (8.6) | 21 (5.3) | 340 (86.1) |
Melatonin | 13 | 404 | 32 (7.9) | 24 (6.1) | 350 (86.6) | |
12 | Vehicle | 21 | 366 | 41 (11.2) | 33 (9.0) | 301 (79.8) |
Melatonin | 17 | 390 | 36 (9.7) | 27 (6.9)* | 339 (83.4)* |