Table 3 Number and type of examinations recommended in German2,3, US27,28 and European guidelines;29,30.

From: Cumulative radiation exposure from imaging procedures and associated lifetime cancer risk for patients with lymphoma

Country

Type of lymphoma

Initial workup

Number of examinations during

Therapy

Follow-up (5 years)

Refractory disease

Germany

HL

1 Chest X-ray

2 CTs Neck/Thorax/Abdomen

Only in clinical relapse

1 CT Neck/Thorax/Abdomen

1 CT Neck/Thorax/Abdomen

DLBCL

1 CT Neck/Thorax/Abdomen

1 CT Neck/Thorax/Abdomen, 1 PET/CT or CT Neck/Thorax/Abdomena

Not in routine follow-up

None

USA

HL

1 Chest X-ray 1 PET/CT or CT Neck/Thorax/Abdomen

1-2 PET/CTs or CTs Neck/Thorax/Abdomenb

2-4 Chest-X-raysb or CTs

1 PET/CT or CT

DLBCL

1 CT Thorax/Abdomen and/or 1 PET/CT

2 PET/CTs or 1 PET/CT and 1 CT Neck/Thorax/Abdomen

0-4 CTs Neck/Thorax/Abdomenc

None

Europe

HL

1 Chest X-ray 1 PET/CT or CT Neck/Thorax/Abdomen

1 CT Neck/Thorax/Abdomen, 1 PET/CT or CT Neck/Thorax/Abdomen

Only if clinical symptoms occur

Not specified

DLBCL

1 CT Neck/Thorax/Abdomen and 1 PET/CT

1 PET/CT, 1 CT Neck/Thorax/Abdomen or PET/CT

Not in routine follow-up

1 CT Neck/Thorax/Abdomen and 1 PET/CT

  1. Note: aPET/CT not paid by german statutory health insurance, otherwise PET/CT would be recommended; bdepending on tumor response; cdepending on initial stage.
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