Table 1 Echocardiographic characteristics of mice 0 or 14 days after TAC surgery.

From: Aberrant Splicing Promotes Proteasomal Degradation of L-type CaV1.2 Calcium Channels by Competitive Binding for CaVβ Subunits in Cardiac Hypertrophy

 

Baseline

Day 14 post-TAC

Heart rate (bpm)

421 ± 22

479 ± 21*

LVAW; d (mm)

0.74 ± 0.03

1.15 ± 0.04§

LVAW; s (mm)

1.00 ± 0.05

1.41 ± 0.06§

LVPW; d (mm)

0.55 ± 0.02

0.96 ± 0.06§

LVPW; s (mm)

0.70 ± 0.04

1.10 ± 0.07§

LVID; d (mm)

4.25 ± 0.08

4.11 ± 0.12

LVID; s (mm)

3.35 ± 0.15

3.49 ± 0.13

LVEF (%)

49.53 ± 2.90

33.86 ± 2.53#

FS (%)

25.05 ± 1.82

16.18 ± 1.45#

CO (ml/min)

16.68 ± 1.11

12.08 ± 1.04#

LV mass (mg)

74.29 ± 2.52

135.50 ± 11.06§

  1. Echocardiography of mice 0 or 14 days after TAC surgery (n = 6). LVAW, left ventricle anterior wall thickness at end diastole (d) or end systole (s); LVPW, left ventricle posterior wall thickness; LVID, left ventricle internal dimension; LVEF, left ventricle ejection fraction; FS, fraction shortening; CO, cardiac output. *p < 0.05, #p < 0.01, §p < 0.001.
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