Figure 7
Homoarginine metabolism in AGXT2 transgenic mice.
Plasma homoarginine (A) and 6-guanidino-2-oxocaproic acid (GOCA) (B) levels in wild type (wt) and alanine-glyoxylate aminotransferase 2 transgenic (AGXT2 Tg) mice; ***P < 0.001 vs wt. mRNA levels of alanine-glyoxylate aminotransferase 2 (Agxt2), L-arginine: glycine amidinotransferase (Agat) and guanidinoacetate N-methyltransferase (Gamt) in the liver (C) and kidney (D) of AGXT2 Tg and wt mice. ***P < 0.001; **P < 0.01.
