Figure 4

Loss of cydAB, hmp, norVW, and ytfE diminishes survival within primed macrophages.
(A) Survival data using primed macrophages after 2 h are expressed as a % of intracellular bacteria at 20 min post-infection. (B) Control data with unprimed macrophages (experiments performed as in panel A) showing that loss of cydAB or hmp does not diminish survival. Data are representative of 3 independent infections, and error bars represent SEM. Asterisks indicate data that are significantly different from WT (Student’s t-test, P < 0.05).