Table 2 Measured TCR/pMHCI equilibrium binding affinities (KDeq) for the CD8+ T-cell clones used in this study.

From: Targeted suppression of autoreactive CD8+ T-cell activation using blocking anti-CD8 antibodies

TCR

Specificity

HLA restriction

Minimal epitope

KDeq (μM)

1E6

PPI

A*0201

ALWGPDPAAA

27831,32

1E6

PPI

A*0201

RQWGPDPAAV

1041

3F2

PPI

A*0201

ALWGPDPAAA

>25073

4C6

PPI

A*2402

LWMRLLPLL

10073

SB27

EBV

B*3508

LPEPLPQGQLTAY

9.943,44