Table 1 Univariable and multivariable measures of pre-operative factors associated with post-operative olfactory outcome.
From: Longer latency of sensory response to intravenous odor injection predicts olfactory neural disorder
Variable | N = 253 | Mean (pre) | Mean (post) | Univariable OR (95% CI) | p-value | Multivariable OR (95% CI) | p-value |
|---|---|---|---|---|---|---|---|
age (years) |  | 45.4 ± 13.89 |  | 1.01 (0.99–1.03) | 0.26 |  |  |
sex | male 179 (71%) |  |  | 0.85 (0.49–1.49) | 0.58 |  |  |
female 74 (29%) | |||||||
primary or revision | primary 198 (78%) |  |  | 0.95 (0.52–1.76) | 0.88 |  |  |
revision 55 (22%) | |||||||
CRS with/without polyp | with polyp 186 (74%) |  |  | 1.22 (0.7–2.15) | 0.49 |  |  |
without polyp 67 (26%) | |||||||
Likart scale score (sense of smell) |  | 3.8 ± 1.9 | 1.4 ± 1.5 |  |  |  |  |
Likart scale score (nasal discharge) |  | 2.8 ± 1.7 | 0.8 ± 1.1 | 0.99 (0.87–1.14) | 0.92 |  |  |
Likart scale score (nasal obstruction) |  | 3.8 ± 1.6 | 0.7 ± 0.9 | 0.98 (0.85–1.12) | 0.78 |  |  |
IVO (relative onset latency) |  | 1.8 ± 0.8 |  | 2.34 (1.53–3.56) | 0.0001 | 2.22 (1.43–3.44) | 0.0004 |
IVO (relative duration) |  | 0.9 ± 0.2 |  | 0.69 (0.2–2.3) | 0.55 |  |  |
T & T olfactometry score (detection) |  | 3.5 ± 1.9 |  | 1.11 (0.97–1.26) | 0.14 | 1.1 (0.83–1.44) | 0.53 |
T & T olfactometry score (recognition) |  | 4.1 ± 1.5 |  | 1.11 (0.94–1.31) | 0.2 | 0.94 (0.66–1.34) | 0.74 |
CT score (total) |  | 10.2 ± 5.5 |  | 1.01 (0.96–1.05) | 0.83 |  |  |
 maxillary sinus | 2.0 ± 0.9 | 1.05 (0.79–1.41) | 0.73 | ||||
 anterior ethmoidal sinus | 2.3 ± 1.0 | 0.95 (0.75–1.22) | 0.7 | ||||
 posterior ethmoidal sinus | 1.9 ± 1.1 | 1.11 (0.89–1.39) | 0.37 | ||||
 sphenoid sinus | 1.1 ± 1.3 | 1.13 (0.93–1.38) | 0.23 | ||||
 frontal sinus | 1.7 ± 1.4 | 0.97 (0.81–1.17) | 0.78 | ||||
 ostiomeatal complex | 1.1 ± 1.6 | 0.95 (0.82–1.2) | 0.56 | ||||
IgE |  | 246.7 ± 437.8 |  | 1.0 (0.99–1.0) | 0.91 |  |  |
% eosinophils |  | 6.2 ± 4.7 |  | 1.02 (0.96–1.07) | 0.56 |  |  |
number of eosinophils (/μL) |  | 371.0 ± 325.8 |  | 1.0 (0.99–1.0) | 0.61 |  |  |
allergic rhinitis | yes 121 (48%) |  |  | 1.05 (0.63–1.74) | 0.85 |  |  |
no 132 (52%) | |||||||
asthma | yes 41 (16%) |  |  | 1.29 (0.64–2.6) | 0.48 |  |  |
no 212 (84%) | |||||||
diabetes mellitus | yes 14 (6%) |  |  | 0.85 (0.29–2.53) | 0.77 |  |  |
no 239 (94%) | |||||||
smoking | current smoke 61 (24%) |  |  | 0.94 (0.52–1.68) | 0.82 |  |  |
non-smoker 192 (76%) | |||||||
brinkman index | 449.5 ± 505.1 |  | 1.0 (1.0–1.001) | 0.2 | 1.0 (1.0–1.001) | 0.48 |
