Table 1 Definition of variables.
From: Prognosis of alcohol-associated lactic acidosis in critically ill patients: an 8-year study
Variable | Definition |
|---|---|
Alcohol abuse | Uncontrolled alcohol drinking despite adverse consequences such as hepatic toxicity. |
Hypoglycemic event | Plasma glucose <70 mg/dL with or without symptoms27. |
Acute kidney injury | At least 1.5 times increase in baseline serum creatinine. |
Chronic kidney disease | Baseline serum creatinine ≧1.5 mg/dL for men and ≧1.4 mg/dL for women. |
Liver disease | The presence of liver cirrhosis or hepatitis. Cirrhosis is diagnosed according to clinical manifestations, laboratory results and image studies; and hepatitis is diagnosed using the evidence regarding abnormal hepatic biochemical and functional tests. |
Sepsis | The presence of infection together with systemic manifestations of infection. |
High MCV | MCV >100 fL (normal range of MCV: 80–100 fL). |
Hyperammonemia | Serum ammonia level >32 μmol/L (normal range of ammonia level: 11–32 μmol/L). |
Lactate clearance rate per hour | 100% × [(peak blood lactate level - dynamic blood lactate level when blood lactate concentration <5 mmol/L)/(peak blood lactate level)]/(time interval by hours spent between the peak and dynamic blood lactate level). |
