Table 3 The comparison between survivors and non-survivors.

From: Prognosis of alcohol-associated lactic acidosis in critically ill patients: an 8-year study

Characteristics

Survivors Median/IRQ (min~max)

Non- survivors Median$ (min~max)

p

No. of patients

21

2

 

Age (years)

51.0/10.5 (32–78)

45.5 (40–51)

0.561

Sex, male, n (%)

20 (95.2%)

2 (100%)

1.000

APACHE II score

14.0/10 (7–33)

20.5 (17–24)

0.176

Peak lactate level (mmol/L)

17.8/8.8 (9.7–35.8)

14.6 (13.3–15.9)

0.711

Lactate clearance rate per hour

7.4/6.9 (3.0–25.3)

3.5 (2.8–4.3)

0.047*

Nadir arterial pH

7.2/0.3 (6.8–7.5)

7.45 (7.4–7.5)

0.042*

Nadir arterial bicarbonate level (mmol/L)

8.2/8.5 (2.3–21.1)

15.5 (13.3–17.6)

0.158

Detectable blood or urine ketone body, n (%)

15 (78.9%)

0 (0%)

0.250

Detectable serum alcohol level, n (%)

10 (71.4%)

Hypoglycemia, n (%)

2 (9.5%)

0 (0%)

1.000

Hyperammonemia, n (%)

15 (71.4%)

2 (100%)

1.000

High MCV, n (%)

13 (61.9%)

1 (50%)

1.000

Gastrointestinal bleeding, n (%)

4 (19%)

1 (50%)

0.395

Sepsis, n (%)

9 (42.9%)

2 (100%)

0.217

Acute kidney injury, n (%)

15 (71.4%)

1 (50%)

0.526

Chronic kidney disease, n (%)

2 (9.5%)

0 (0%)

1.000

Liver cirrhosis, n (%)

7 (33.3%)

2 (100%)

0.142

Hepatitis, n (%)

4 (19%)

0 (0%)

1.000

Vasoactive support, n (%)

3 (14.3%)

0 (0%)

1.000

Mechanical ventilation support, n (%)

0 (0%)

2 (100%)

<0.05*

Renal replacement therapy, n (%)

1 (4.8%)

0 (100%)

1.000

  1. Wilcoxon rank-sum tests were used for continuous variables and Fisher’s exact tests was used for categorical variables.
  2. *A statistically significant between-group difference (P < 0.05).
  3. $Due to only 2 cases, no IQR performed.