Table 3 Systemic insulin resistance and inflammatory markers following conventionalization of germ-free mice by SF and CTL fecal microbiome.

From: Chronic Sleep Disruption Alters Gut Microbiota, Induces Systemic and Adipose Tissue Inflammation and Insulin Resistance in Mice

 

TF-SF (n = 8)

TF-CTL (n = 8)

Non-TF Germ-Free (n = 4)

P-value (TF-SF vs. TF-CTL or Non-TF)

HOMA-IR

6.2 ± 2.5

3.4 ± 1.4

3.4 ± 1.5

<0.01

NGAL (ng/ml)

198.4 ± 46.8

77.6 ± 35.7

64.3 ± 45.1

<0.01

LBP (ng/ml)

112.6 ± 23.8

44.9 ± 22.1

27.9 ± 20.2

<0.01

IL-6 (pg/ml)

35.4 ± 8.4

19.5 ± 7.2

12.6 ± 5.5

<0.05

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