Figure 4
From: A unique peptide deformylase platform to rationally design and challenge novel active compounds
3D comparison of the binding between various PDFIs and actinonin.
(a) Overall superimposition of actinonin, AT002, AT019, AT020, AB47, SMP289 and RAS358. The color code used is that of Fig. 1a for SaPDF and Fig. 3 for PDFIs. Two distinct orientations are displayed. (b) Comparison of the Tyr167 side chain position of SaPDF in complex with AB47 (pink) or SMP289 (orange).
