Figure 1
Extensive lysine methylation occurs at asexual blood stages of P. falciparum.
Anti-methyl-lysine specific antibodies recognize the proteins from three different blood stages of P. falciparum. (A) Representative western blot showing extent of lysine methylation at ring, trophozoite and schizont stages when the parasite lysates were probed with anti-methyl-lysine specific antibody. (B) The same antibodies also immuno-stained the asexual blood stages of the parasite as examined through immuno-fluorescence assay. The representative confocal microscopy images are shown above. DIC- bright field, DAPI-stained nucleus (blue), immunofluorescent cells labeled with anti-Methyl lysine antibody (green), and merged images.
