Figure 2

Tgfbr1iko recapitulates a spectrum of pathologies that are typical of aortic aneurysmal degeneration.
(A) Masson’s (left column) and Movat’s (right column) staining of cross sections of Tgfbr1iko ATAs that were collected at d28. Arrows and symbols point to the pathology specified on the side of the columns. The boxed area is amplified in the lower panels to show structural details of the medial thinning. (B) Histology representative of Tgfbr1f/f controls. Scale bars: 100 μm.