Figure 6
From: Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine
Antibiotic-treated mice exhibit alterations in Bdnf and Ntrk2 transcripts in the NAc.
(a) In mice treated with antibiotics and cocaine compared to controls levels of Bdnf were significantly elevated in antibiotic-treated (Abx) animals (*p < 0.05; n = 9–11/group); control animals, H2O. (b) Transcripts encoding the receptor for BDNF were also examined. Levels of Ntrk2 were significantly decreased specifically in antibiotic and cocaine-treated animals (**p < 0.01; n = 9–11/group).
