Table 1 Prevalence, 95% confidence intervals, and mean fluorescence intensity of IgG responses to PvGAMA-Ecto fragment in vivax malaria patients and healthy individual serum samples.

From: Plasmodium vivax GPI-anchored micronemal antigen (PvGAMA) binds human erythrocytes independent of Duffy antigen status

Patients/healthy from each country

No. of samples

Positive

Negative

Total (%)a

95% CIb

MFIc

p valuee

Patients

 Korea

23

27

50 (46.0)

32.9–59.6

12139.2

p < 0.0001

 Myanmar

44

6

50 (88.0)

76.2–94.4

18986.9

p < 0.0001

 Thailand

29

8

37 (78.4)

62.8–88.6

19039.2

p < 0.0001

 China

17

3

20 (85.0)

64.0–94.8

25453.1

p < 0.0001

 Total

113

44

157 (72.0)

64.5–78.4

17642.1

 

Healthy individuals

 Korea

2

48

50 (96.0)

86.5–98.9

3540.2

 
  1. aSensitivity: percentage of positive in patient samples.
  2. bCI: confidence interval.
  3. cMFI: mean fluorescence intensity.
  4. dSpecificity: percentage of negative in healthy samples.
  5. eDifferences in the total IgG prevalence for each antigen between vivax patients and healthy individuals were calculated by Student’s t-test. A p value of < 0.05 is considered statistically significant.
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