Table 2 Correlations between RBC concentrations of total MTXPGs and variable clinical parameters in patients with RA receiving MTX therapy.

From: Folylpolyglutamate synthase is a major determinant of intracellular methotrexate polyglutamates in patients with rheumatoid arthritis

 

Total MTXPGs

Univariate model

 

Multivariate model

β

p value

R2

β

p value

Sex

0.019

0.761

0.019

−0.014

0.822

Duration

0.012

0.842

0.012

0.127

0.095

Dose of methotrexate

0.399

0.000

0.156

0.421

0.000

Age

0.102

0.099

0.007

0.162

0.081

Stage

0.102

0.112

0.112

−0.019

0.802

DAS28-ESR

0.091

0.147

0.004

0.049

0.432

R2

   

0.180

 
  1. β: regression coefficient; Stage; Steinblocker’s classification of progression; DAS28-ESR: disease activity score-erythrocyte sedimentation rate; R2: coefficient of determination.
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