Table 2 Effects of MES + HS over time compared with baseline.
Adiposity | ||||
---|---|---|---|---|
Baseline | MES + HS | delta | p value | |
Visceral Fat Area (cm2) | 166.12 ± 7.75 | 154.44 ± 6.76 | −11.69 | ** |
SubQ Fat Area (cm2) | 207.11 ± 11.95 | 204.04 ± 12.14 | −3.07 | 0.205 |
total Fat Area (cm2) | 373.23 ± 16.47 | 358.48 ± 16.07 | −14.75 | ** |
BMI (kg/m2) | 29.14 ± 0.56 | 28.88 ± 0.58 | −0.25 | ** |
Wc (cm) | 100.10 ± 1.33 | 97.86 ± 1.23 | −2.24 | ** |
Glucose control and insulin resistance | ||||
Fasting plasma glucose (mg/dL) | 159.38 ± 5.30 | 144.45 ± 4.21 | −14.93 | ** |
Fasting IRI (µIU/mL) | 9.77 ± 0.74 | 7.91 ± 0.59 | −1.86 | ** |
HOMA-IR | 4.08 ± 0.42 | 2.99 ± 0.29 | −1.09 | ** |
HbA1c (%) | 7.64 ± 0.08 | 7.28 ± 0.08 | −0.36 | ** |
GA (%) | 19.15 ± 0.41 | 18.40 ± 0.39 | −0.75 | ** |
Adiponectin (µg/mL) | 7.54 ± 0.47 | 8.47 ± 0.54 | 0.93 | ** |
Blood pressure | ||||
Systolic Blood Pressure (mmHg) | 134.43 ± 1.84 | 132.08 ± 1.83 | −2.35 | * |
Diastolic Blood Pressure (mmHg) | 78.38 ± 1.27 | 77.10 ± 1.40 | −1.28 | 0.139 |
Heart Rate (bpm) | 76.85 ± 1.68 | 75.02 ± 1.44 | −1.83 | 0.052 |
Systemic inflammation | ||||
TNF-α (pg/mL) | 1.64 ± 0.11 | 1.24 ± 0.08 | −0.40 | ** |
IL-6 (pg/mL) | 3.17 ± 0.29 | 2.78 ± 0.31 | −0.44 | 0.105 |
hs-CRP (ng/mL) | 1968.77 ± 442.90 | 1305.17 ± 246.04 | −663.60 | ** |
WBC (/µL) | 6751.67 ± 204.86 | 6315.00 ± 183.01 | −436.67 | ** |
Renal function | ||||
eGFR (mL/min/1.73 m2) | 76.52 ± 2.23 | 79.48 ± 2.35 | 2.96 | ** |
ACR (µg/gCre) | 75.20 ± 20.87 | 56.47 ± 15.82 | −18.73 | * |
L-FABP (mg/gCr) | 5.42 ± 0.53 | 4.38 ± 0.49 | −1.04 | ** |
Hepatic steatosis and lipids | ||||
AST/ALT | 0.86 ± 0.03 | 0.92 ± 0.04 | 0.06 | ** |
UA (mg/dL) | 5.58 ± 0.19 | 5.43 ± 0.18 | −0.15 | * |
LDL-C (mg/dL) | 109.30 ± 3.54 | 105.80 ± 3.45 | −3.50 | 0.055 |
HDL-C (mg/dL) | 52.48 ± 1.84 | 52.92 ± 1.65 | 0.43 | 0.354 |
TG (mg/dL) | 183.40 ± 18.75 | 153.38 ± 12.46 | −30.02 | * |
FFA (µEq/L) | 635.62 ± 30.80 | 584.02 ± 25.73 | −51.60 | 0.064 |