Table 5 Evaluation of SNPs in clinical isolates.
Genes_SNPs | Single-base mutation | Verification in clinical isolates (Resistant isolates [R], n = 21; Susceptible isolates [S], n = 52) | P value |
|---|---|---|---|
rumA_619 | C− > T | R: 10/21 S: 2/52 | <0.0001 |
rplF_140 | T− > C | R: 8/21 S: 1/52 | <0.0001 |
MCR_0020_643 | G− > A | R: 8/21 S: 0/52 | <0.0001 |
MCR_1465_270 | T− > G | R: 4/21 S: 0/52 | 0.0055 |
copB_1348 | C− > A | R: 9/21 S: 8/52 | 0.0292 |
rrmA_238 | G− > A | R: 6/21 S: 2/52 | 0.0058 |
23S rRNA_2330 | A− > T | R: 21/21 S: 0/52 | <0.0001 |
23S rRNA_2480 | C− > T | R: 13/21 S: 0/52 | <0.0001 |
23S rRNA_2144 | A− > T | R: 3/21 S: 0/52 | 0.0214 |
MCR_0016_1249 | A− > G | R: 3/21 S: 2/52 | 0.1395 |
MCR_1465_695 | G− > A | R: 13/21 S: 31/52 | 1.0000 |
copB_1205 | A− > C | R: 15/21 S: 23/52 | 0.0680 |
