Figure 8 | Scientific Reports

Figure 8

From: Novel Natural Product-like Caged Xanthones Bearing a Carbamate Moiety Exhibit Antitumor Potency and Anti-Angiogenesis Activity In vivo

Figure 8

8n had anti-angiogenesis activity in vitro and in vivo.

(A) A wound-healing assay was used to evaluate the motility of HUVECs after treatment with 8n for 24 h. (B) Changes in cell motility were evaluated using a transwell assay of cell migration and invasion. (C) The effect of 8n on tube formation by HUVECs. HUVECs were incubated with 8n for 6 h and then transferred to Matrigel for 6 h. (D) Zebrafish embryos treated with blank control or 1, 10, or 50 μg/ml of 8n.

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