Figure 1 | Scientific Reports

Figure 1

From: Optical manipulation of the alpha subunits of heterotrimeric G proteins using photoswitchable dimerization systems

Figure 1

The present approach for manipulating Ca2+ via Gαq using the Magnet system.

(A) Light-inducible dimerization of the Magnet system allows Gαq to translocate to the plasma membrane and trigger cytosolic Ca2+ release through the phospholipase C-beta (PLCβ)-inositol triphosphate receptor (IP3R) pathway. (B) Constructs for nMagHigh1-mKikGR-CAAX and pMagFast1-Gαq.

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