Table 2 IC50 values obtained from dose–response curves to cisplatin in HSC3, SCC3 and TCA8113 cells following 48-h treatment with cisplatin (0–90 uM) and incubation in hypoxia or hypoxia with the treatment of si-HIF-1α.

From: Metformin sensitizes the response of oral squamous cell carcinoma to cisplatin treatment through inhibition of NF-κB/HIF-1α signal axis

 

Control(pO21%)

si-HIF-1α(pO21%)

HSC3

17.48 ± 1.17

9.60 ± 1.00

SCC3

9.52 ± 1.11

2.37 ± 0.16

TCA8113

10.82 ± 1.51

6.97 ± 1.65

  1. (Means ± s.e.m. of 3 independent experiments).
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