Table 2 Total binding energies and contact area values obtained for SEQ1-SEQ5, and shown in Fig. 2.

From: Synthetic oligonucleotide antigens modified with locked nucleic acids detect disease specific antibodies

Sequence

E TX … Protein (kcal/mol)

E DNA … Protein (kcal/mol)

S (Å2)

n

SEQ1

−64.2 ± 8.5

−522.1 ± 97.5

771.3 ± 103.4

2001

SEQ2

−46.1 ± 3.7

−438.3 ± 112.9

674.1 ± 82.2

2001

SEQ3

−63.2 ± 6.9

−519.4 ± 61.8

630.2 ± 40.2

786

SEQ4

−65.1 ± 4.1

−552.1 ± 71.7

680-7 ± 62.1

1774

SEQ5

−52.1 ± 5.3

−578.9 ± 82.9

748.8 ± 57.9

1812

  1. Note that the values in Fig. 2 are plotted relative to the smallest value of energy or the contact area. Additionally, the number of points (n) used in the averaging for SEQ1-SEQ5 is indicated.