Table 1 Clinical parameters of the study subjects. Data are expressed as mean ± SD.
Parameters | Non-diabetic control (NDC) (n = 27) | Type 2 Diabetes (T2D) (n = 24) | Type 1 Diabetes (T1D) (n = 14) | p values |
|---|---|---|---|---|
Sex (M/F) | 16/11 | 15/9 | 8/6 | |
Age (Years) | 31.7 ± 8.9 | 36.2 ± 11.7 | 21.7 ± 13.8 | <0.001* |
Weight (kg) | 61.2 ± 7.2 | 60.1 ± 5.8 | 47.1 ± 11.8 | <0.001* |
BMI (kg/m2) | 23.9 ± 2.4 | 24.6 ± 2.3 | 19.4 ± 2.9 | <0.001* |
Fasting Plasma Glucose (mg/dL) | 87.7 ± 9.8 | 132.08 ± 12.2 | 272.6 ± 107.6 | <0.001* |
Fasting Plasma Insulin (μIU/mL) | 9.68 ± 3.1 | 5.2 ± 1.3 | 1.1 ± 0.7 | <0.001* |
2-hr Post-dose Plasma Glucose (mg/dL) | 126.6 ± 10.3 | 269.8 ± 37.9 | 452 ± 99.9 | <0.001* |
HbA1c (%) | 5.2 ± 0.2 | 7.5 ± 0.5 | 11.3 ± 2.9 | <0.001* |
Fasting CA Activity (U/min/mL) | 8.9 ± 1.3 | 5.2 ± 1.3 | 3.1 ± 1.4 | <0.001* |
Post-dose CA Activity (U/min/mL) | 7.5 ± 1.36 | 11.1 ± 2.8 | 4.5 ± 1.9 | <0.001* |