Table 1 Clinical parameters of the study subjects. Data are expressed as mean ± SD.

From: Targeting erythrocyte carbonic anhydrase and 18O-isotope of breath CO2 for sorting out type 1 and type 2 diabetes

Parameters

Non-diabetic control (NDC) (n = 27)

Type 2 Diabetes (T2D) (n = 24)

Type 1 Diabetes (T1D) (n = 14)

p values

Sex (M/F)

16/11

15/9

8/6

 

Age (Years)

31.7 ± 8.9

36.2 ± 11.7

21.7 ± 13.8

<0.001*

Weight (kg)

61.2 ± 7.2

60.1 ± 5.8

47.1 ± 11.8

<0.001*

BMI (kg/m2)

23.9 ± 2.4

24.6 ± 2.3

19.4 ± 2.9

<0.001*

Fasting Plasma Glucose (mg/dL)

87.7 ± 9.8

132.08 ± 12.2

272.6 ± 107.6

<0.001*

Fasting Plasma Insulin (μIU/mL)

9.68 ± 3.1

5.2 ± 1.3

1.1 ± 0.7

<0.001*

2-hr Post-dose Plasma Glucose (mg/dL)

126.6 ± 10.3

269.8 ± 37.9

452 ± 99.9

<0.001*

HbA1c (%)

5.2 ± 0.2

7.5 ± 0.5

11.3 ± 2.9

<0.001*

Fasting CA Activity (U/min/mL)

8.9 ± 1.3

5.2 ± 1.3

3.1 ± 1.4

<0.001*

Post-dose CA Activity (U/min/mL)

7.5 ± 1.36

11.1 ± 2.8

4.5 ± 1.9

<0.001*

  1. *Represents statistically significant differences (p < 0.05) among non-diabetic control (NDC), type 2 diabetes (T2D) and type 1 diabetes (T1D). The abbreviations M and F stand for male and female, respectively.