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Figure 2

From: Crystal structures and inhibition of Trypanosoma brucei hypoxanthine–guanine phosphoribosyltransferase

Figure 2

Sequence and structure of TbrHGPRT.

(A) Subunit structure of TbrHGPRT in complex with GMP. Two sulfate ions and two magnesium ions (blue spheres) are also observed in the structure. (B) Comparison of the amino sequences of TbrHGPRT, TcrHGPRT and human HGPRT. The coloured regions in the sequence alignment (B) correlate with the coloured regions in the structural image (A).

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