Figure 4 | Scientific Reports

Figure 4

From: Crystal structures and inhibition of Trypanosoma brucei hypoxanthine–guanine phosphoribosyltransferase

Figure 4

Stereoimages of the comparison of the active sites of the TbrHGPRT.GMP and MtHGPRT.GMP.PPi complexes.

(A) Connolly surface for the polypeptide of the TbrHGPRT.GMP complex with the ligands from the TbrHGPRT.GMP complex (green carbon atoms) and the MtHGPRT.GMP.PPi complex (yellow carbon atoms) overlayed. (B) Superimposition of the TbrHGPRT.GMP complex (green carbon atoms) and the MtHGPRT.GMP.PPi complex (yellow carbon atoms).

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