Figure 1
From: von Willebrand factor contributes to poor outcome in a mouse model of intracerebral haemorrhage
Release of VWF after autologous blood induced intracerebral haemorrhage.
(A) Mice were subjected to either intracerebral hemorrhage (ICH) or sham surgery. At 24 hours after surgery, plasma samples were taken and analyzed for VWF antigen levels. Values are means ± standard errors of the means (n = 6), *P < 0.05. (B) Representative image of VWF immunostaining. VWF was upregulated in the hemorrhagic regions, especially in the perihematomal regions of the brain. (C) Double immunostaining of VWF with endothelial cells (CD31) in the perihematomal area. Bar = 200 μm (B) and 20 μm (C). LV, lateral ventricle; CTX, cortex.
