Figure 8
From: Multifunctional Cu2−xTe Nanocubes Mediated Combination Therapy for Multi-Drug Resistant MDA MB 453
Combinatorial therapeutic approach (Chemo-PDT-PTT).
The therapeutic nanoformulations at a concentration of 0.05 mg/mL for chemo (PEG-NCs-DOX), PDT (PEG-NCs-DOX + 2 min laser exposure) and PTT (PEG-NCs-DOX + 10 min laser exposure) exhibited reduced cell proliferation (Ki-67 panel in a; b) and increased apoptotic signals (Annexin-V panel in a; c) when compared to controls. Cell proliferation was evaluated after immunofluorescent staining with Ki-67 marker whereas the apoptosis was analyzed using Annexin-V. Error bars indicate SE.
