Figure 4

The Oral Glucose Input function.
Panels (A–C) show the output of the OGI function layered by different MMTs. The OGI function, i.e. the predicted glucose rate of appearance in the bloodstream at each time point after the MMT ingestion, is provided as mean ± SEM of the individual OGI values for the study patients undergoing the MMT1 and MMT2 and is expressed as mg/Kg/min (see Figure S12 for the same panels expressed as μmol/min). Curves’ shapes and peaks are consistent with literature’s analogous functions26. Detailed description of the function can be found in Supplementary Material.