Figure 3

MALAT1 combined with HULC promotes liver cancer stem cell growth in vivo.
(a) The mice were stratified and the tumors were recovered. The photography of xenograft tumors in the four groups (indicated in left). (b) The wet weight of each tumor was determined for each mouse. Each value was presented as mean ± standard error of the mean (SEM). (c) The Xenograft appearance time (days). Each value was presented as mean ± standard error of the mean (SEM). (d,a) A portion of each tumor was fixed in 4% paraformaldehyde and embedded in paraffin for histological hematoxylin-eosin (HE) staining (upper) and anti-PCNA immunostainning (lower). (original magnification × 100). (b) PCNA positive cells analysis. Each value was presented as mean ± standard error of the mean (SEM).