Figure 3

Results of the right finger-tapping task during four BOLD fMRI scans before and after 1-Hz rTMS of the left (A) and right M1 (B). Group one sample t-test maps had no threshold to show time course of changes in whole brain neural activity. (A) A time course of BOLD activity in the left M1 showed positive BOLD signal (activation) during right finger-tapping in four conditions (pre, post1, post2, and post3). The mean percent signal change was slightly reduced at post1 and post2, but returned to the pre-rTMS value. The reduction in percent signal change at post1 and post2 was not statistically significant. (B) Time course of BOLD activity in the right M1 showed negative BOLD signal (deactivation) during right finger-tapping at four conditions (pre, post1, post2 and post3). Deactivation was slightly increased at post1, post2, and post3, but there was no statistical significance. Plots showed means (lines) and SEMs (shading) of percentage signal changes.