Figure 2
From: Targeting inflammasome/IL-1 pathways for cancer immunotherapy
Effects of NLRP3 on tumor growth and metastasis.
(A) WT and NLRP3 KO mice (n = 6) were injected orthotopically with EO771 mammary tumor cells. Tumor growth was measured. (B) and (C). PyT8 murine mammary tumor cells were implanted into 4th fat pads of WT and NLRP3 KO female mice (n = 8). Tumor growth and lung metastasis were measured. *P < 0.05, **P < 0.01 (Student’s t test). Data are representative of three independent experiments with similar results.
