Figure 4
From: Pollen/TLR4 Innate Immunity Signaling Initiates IL-33/ST2/Th2 Pathways in Allergic Inflammation
IL-33 induction in SRW-induced EAC model requires TLR4 and MyD88.
The mRNA expression of IL-33 and its signaling molecules and Th2 cytokines by corneal epithelium and conjunctiva in EAC model with BALB/c and Tlr4-d mice (A), as well as in C57BL/6 based MyD88+/+ and MyD88−/− mice (B), with PBS-treated mice as controls. Results shown are the Mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001; n = 4, compared with PBS controls; vP < 0.05,vvP < 0.01, n = 4, compared with wild type mice.
