Figure 4
From: Antagonistic autoregulation speeds up a homogeneous response in Escherichia coli
Single-cell dynamics of the mar circuit without being induced.
(A) Model simulation of the stochastic dynamics of MarR [arbitrary units (AU)] in absence of salicylate (left), and also simulations when a cooperative MarA is considered (right, top; the gray curve shows the deterministic dynamics) and when MarA prevents MarR binding (right, bottom). (B) Representative trajectory (YFP) of a single cell. In the inset, the distribution of YFP for all single cells at all time points confirms a unimodal distribution corresponding to a continuous production of MarR [arbitrary units (AU)], and the correlation between YFP and CFP.
